| A voltage-dependent switch underlies efficient yet specific learning and memory |
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Manoim Wolkovitz JE, Tunc IA, (...), Parnas M |
Current Biology |
2026 |
|
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| Local autophagy impairment triggers brain-wide presynaptic remodeling and resilience |
|
Toppe D, Huang S, (...), Sigrist SJ |
EMBO Journal |
2026 |
|
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| Compromising tyrosine hydroxylase function extends and blunts the temporal profile of reinforcement by dopamine neurons in Drosophila |
|
Amin F, König C, (...), Gerber B |
Journal of Neuroscience |
2025 |
|
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| Individual dopaminergic neurons induce unique, yet overlapping combinations of behavioural modulations including safety learning, memory retrieval and acute locomotion |
|
Toshima N, Behrad A, (...), Schleyer M |
bioRxiv |
2025 |
|
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| Enhanced memory despite severe sleep loss in Drosophila insomniac mutants |
|
Huang S, Piao C, (...), Sigrist SJ |
PLOS Biology |
2025 |
|
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| Functional dissection of a neuronal brain circuit mediating higher-order associative learning |
|
Rachad EY, Deimel SH, (...), Fiala A |
Cell Reports |
2025 |
|
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| The innexin 7 gap junction protein contributes to synchronized activity in the Drosophila antennal lobe and regulates olfactory function |
|
Fuenzalida-Uribe N, Hidalgo S, (...), Campusano JM |
Frontiers in Neural Circuits |
2025 |
|
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| A behavioral architecture for realistic simulations of Drosophila larva locomotion and foraging |
|
Sakagiannis P, Jürgensen A, Nawrot MP |
eLife |
2025 |
|
|
| Individual dopaminergic neurons induce unique, yet overlapping combinations of behavioural modulations including safety learning, memory retrieval and acute locomotion |
|
Toshima N, Behrad A, (...), Schleyer M |
eLife |
2025 |
|
|
| Prediction error drives associative learning and conditioned behavior in a spiking model of Drosophila larva |
|
Jürgensen A, Sakagiannis P, Schleyer M, Gerber B, Nawrot MP |
iScience |
2024 |
|
|
| Minimal circuit motifs for second-order conditioning in the insect mushroom body |
|
Jürgensen Anna-Maria, Schmitt Felix Johannes , Nawrot Martin Paul |
Frontiers in Physiology |
2024 |
|
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| Presynaptic regulators in memory formation |
|
Turrel O, Gao L, Sigrist SJ |
Learning & Memory |
2024 |
|
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| What do the mushroom bodies do for the insect brain? Twenty-five years of progress |
|
Fiala A, Kaun KR |
Learning & Memory |
2024 |
|
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| The caloric value of food intake structurally adjusts a neuronal mushroom body circuit mediating olfactory learning in Drosophila |
|
Çoban B, Poppinga H, (...), Fiala A |
Learning & Memory |
2024 |
|
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| An integrative sensor of body states: how the mushroom body modulates behavior depending on physiological context |
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Suárez-Grimalt R, Grunwald Kadow IC, Scheunemann L |
Learning & Memory |
2024 |
|
|
| Skewing information flow through pre- and postsynaptic plasticity in the mushroom bodies of Drosophila |
|
Pribbenow C, Owald D |
Learning & Memory |
2024 |
|
|
| Compromising tyrosine hydroxylase function establishes a delusion-like temporal profile of reinforcement by dopamine neurons in<i>Drosophila</i> |
|
Amin F, König C, (...), Gerber B |
bioRxiv |
2024 |
|
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| Neuronal excitability as a regulator of circuit remodeling |
|
Mayseless O, Shapira G, Rachad EY, Fiala A, Schuldiner O |
Current Biology |
2023 |
|
|
| High-resolution analysis of individual Drosophila melanogaster larvae uncovers individual variability in locomotion and its neurogenetic modulation |
|
Thane M, Paisios E, (...), Schleyer M |
Open Biology |
2023 |
|
|
| Minimal circuit motifs for second-order conditioning in the insect mushroom body |
|
Jürgensen A.-M., Schmitt F.J., Nawrot M.P. |
bioRxiv |
2023 |
|
|
| The mushroom body output encodes behavioral decision during sensory-motor transformation |
|
Arican C, Schmitt F J, Rössler W, Strube-Bloss M F, Nawrot M P |
Current Biology |
2023 |
|
|
| Mushroom body encodes behavioral decision |
|
Arican C, Nawrot MP |
G-Node |
2023 |
|
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| An antagonism between Spinophilin and Syd-1 operates upstream of memory-promoting presynaptic long-term plasticity |
|
Ramesh N, Escher M, (...), Sigrist SJ |
bioRxiv |
2023 |
|
|
| An antagonism between Spinophilin and Syd-1 operates upstream of memory-promoting presynaptic long-term plasticity |
|
Ramesh N, Escher M, (...), Sigrist SJ |
eLife |
2023 |
|
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| (M)Unc13s in Active Zone Diversity: A Drosophila Perspective |
|
Piao C, Sigrist SJ |
Frontiers in Synaptic Neuroscience |
2022 |
|
|
| Visualization of learning-induced synaptic plasticity in output neurons of the Drosophila mushroom body γ-lobe |
|
Hancock CE, Rostami V, Rachad EY, Deimel SH, Nawrot MP, Fiala A |
Scientific Reports |
2022 |
|
|
| Pruning deficits of the developing Drosophila mushroom body result in mild impairment in associative odour learning and cause hyperactivity |
|
Poppinga H, Çoban B, (...), Fiala A |
Open Biology |
2022 |
|
|
| Transient active zone remodeling in the Drosophila mushroom body supports memory |
|
Turrel O, Ramesh N, Escher MJ, Pooryasin A, Sigrist SJ |
Current Biology |
2022 |
|
|
| Age-related decrease in appetitive associative memory in fruit flies |
|
König C, Gerber B |
bioRxiv |
2022 |
|
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| Optogenetically induced reward and ‘frustration’ memory in larval Drosophila melanogaster |
|
Thoener J, Weiglein A, Gerber B, Schleyer M |
Journal of Experimental Biology |
2022 |
|
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| A brain-wide form of presynaptic active zone plasticity orchestrates resilience to brain aging in Drosophila |
|
Huang S, Piao C, Beuschel CB, Zhao Z, Sigrist SJ |
PLOS Biology |
2022 |
|
|
| Postsynaptic plasticity of cholinergic synapses underlies the induction and expression of appetitive and familiarity memories in Drosophila |
|
Pribbenow C, Chen Y, (...), Owald D |
eLife |
2022 |
|
|
| Age-related decrease in appetitive associative memory in fruit flies |
|
König C, Gerber B |
Journal of Experimental Biology |
2022 |
|
|
| Prediction error drives associative olfactory learning and conditioned behavior in a spiking model of Drosophila larva |
|
Jürgensen A, Sakagiannis P, Schleyer M, Gerber B, Nawrot MP |
bioRxiv |
2022 |
|
|
| The mushroom body output encodes behavioral decision during sensory-motor transformation |
|
Arican C, Johannes Schmitt F, Rössler W, Strube-Bloss MF, Nawrot MP |
bioRxiv |
2022 |
|
|
| A mechanistic model for reward prediction and extinction learning in the fruit fly |
|
Springer M, Nawrot MP |
eNeuro |
2021 |
|
|
| A quick and versatile protocol for the 3D visualization of transgene expression across the whole body of larval Drosophila |
|
Kobler O, Weiglein A, Hartung K, Chen Y, Gerber B, Thomas U |
bioRxiv |
2021 |
|
|
| Single neuron activity predicts behavioral performance of individual animals during memory retention |
|
Strube-Bloss MF, D’Albis T, Menzel R, Nawrot MP |
bioRxiv |
2021 |
|
|
| Rapid Ca2+ channel accumulation contributes to cAMP-mediated increase in transmission at hippocampal mossy fiber synapses |
|
Fukaya R, Maglione M, Sigrist SJ, Sakaba T |
Proceedings of the National Academy of Sciences of the United States of America |
2021 |
|
|
| Preparing Adult Drosophila melanogaster for Whole Brain Imaging during Behavior and Stimuli Responses |
|
Woller A, Bandow P, Aimon S, Grunwald Kadow IC |
Journal of Visualized Experiments |
2021 |
|
|
| Antagonistic interactions between two Neuroligins coordinate pre- and postsynaptic assembly |
|
Ramesh N, Escher MJ, (...), Sigrist SJ |
Current Biology |
2021 |
|
|
| eIF5A hypusination, boosted by dietary spermidine, protects from premature brain aging and mitochondrial dysfunction |
|
Liang Y, Piao C, (...), Sigrist SJ |
Cell Reports |
2021 |
|
|
| Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila |
|
Pooryasin A, Maglione M, (...), Sigrist SJ |
Nature Communications |
2021 |
|
|
| Circuit reorganization in the Drosophila mushroom body calyx accompanies memory consolidation |
|
Baltruschat L, Prisco L, (...), Tavosanis G |
Cell Reports |
2021 |
|
|
| A neuromorphic model of olfactory processing and sparse coding in the Drosophila larva brain |
|
Jürgensen AM, Khalili A, Chicca E, Indiveri G, Nawrot MP |
bioRxiv |
2021 |
|
|
| A realistic locomotory model of Drosophila larva for behavioral simulations |
|
Sakagiannis P, Jürgensen AM, Nawrot MP |
bioRxiv |
2021 |
|
|
| A quick and versatile protocol for the 3D visualization of transgene expression across the whole body of larval Drosophila |
|
Kobler O, Weiglein A, Hartung K, Chen Y, Gerber B, Thomas U |
Journal of Neurogenetics |
2021 |
|
|
| Associative learning in larval and adult Drosophila is impaired by the dopamine-synthesis inhibitor 3-Iodo-L-tyrosine |
|
Thoener J, König C, (...), Schleyer M |
Biology Open |
2021 |
|
|
| Dendrite enlightenment. |
|
Tavosanis G |
Current Opinion in Neurobiology |
2021 |
|
|
| Silencing neuronal activity is required for developmental circuit remodeling |
|
Mayseless O, Rachad EY, Shapira G, Fiala A, Schuldiner O |
bioRxiv |
2021 |
|
|
| The anterior paired lateral neuron normalizes odour-evoked activity at the mushroom body calyx |
|
Prisco L, Deimel SH, Yeliseyeva H, Fiala A, Tavosanis G |
bioRxiv |
2021 |
|
|
| The anterior paired lateral neuron normalizes odour-evoked activity in the Drosophila mushroom body calyx |
|
Prisco L, Deimel SH, Yeliseyeva H, Fiala A, Tavosanis G |
eLife |
2021 |
|
|
| A neuromorphic model of olfactory processing and sparse coding in the Drosophila larva brain |
|
Jürgensen A, Khalili A, Chicca E, Indiveri G, Nawrot MP |
Neuromorphic Computing and Engineering |
2021 |
|
|
| Presynaptic Active Zone Plasticity Encodes Sleep Need in Drosophila |
|
Huang S, Piao C, Beuschel CB, Götz T, Sigrist SJ |
Current Biology |
2020 |
|
|
| Recurrent architecture for adaptive regulation of learning in the insect brain |
|
Eschbach C, Fushiki A, (...), Zlatic M |
Nature Neuroscience |
2020 |
|
|
| The Unc13A isoform is important for phasic release and olfactory memory formation at mushroom body synapses. |
|
Woitkuhn J, Ender A, (...), Sigrist SJ |
Journal of Neurogenetics |
2020 |
|
|
| Stochastic and Arbitrarily Generated Input Patterns to the Mushroom Bodies Can Serve as Conditioned Stimuli in Drosophila |
|
Warth Pérez Arias CC, Frosch P, Fiala A, Riemensperger TD |
Frontiers in Physiology |
2020 |
|
|
| Visualization of a Distributed Synaptic Memory Code in the Drosophila Brain |
|
Bilz F, Geurten BRH, Hancock CE, Widmann A, Fiala A |
Neuron |
2020 |
|
|
| Circuit and Cellular Mechanisms Facilitate the Transformation from Dense to Sparse Coding in the Insect Olfactory System |
|
Betkiewicz R, Lindner B, Nawrot MP |
eNeuro |
2020 |
|
|
| Identification of Dopaminergic Neurons That Can Both Establish Associative Memory and Acutely Terminate Its Behavioral Expression |
|
Schleyer M, Weiglein A, (...), Gerber B |
Journal of Neuroscience |
2020 |
|
|
| Valence and State-Dependent Population Coding in Dopaminergic Neurons in the Fly Mushroom Body |
|
Siju K, Štih V, Aimon S, Gjorgjieva J, Portugues R, Grunwald Kadow IC |
Current Biology |
2020 |
|
|
| Aversive teaching signals from individual dopamine neurons in larval Drosophila show qualitative differences in their temporal 'fingerprint' |
|
Weiglein A, Thoener J, (...), Gerber B |
Journal of Comparative Neurology |
2020 |
|
|
| Immune Receptor Signaling and the Mushroom Body Mediate Post-ingestion Pathogen Avoidance |
|
Kobler JM, Rodriguez Jimenez FJ, Petcu I, Grunwald Kadow IC |
Current Biology |
2020 |
|
|
| A spiking neural program for sensorimotor control during foraging in flying insects |
|
Rapp H, Nawrot MP |
Proceedings of the National Academy of Sciences of the United States of America |
2020 |
|
|
| Associative learning in larval and adult Drosophila is impaired by the dopamine-synthesis inhibitor 3-Iodo-L-tyrosine |
|
Thoener J, König C, (...), Schleyer M |
bioRxiv |
2020 |
|
|
| A plausible mechanism for Drosophila larva intermittent behavior |
|
Sakagiannis P, Aguilera M, Nawrot MP |
bioRxiv |
2020 |
|
|
| Visualization of naive and learned odor representations using in vivo calcium imaging and immunohistochemical bouton mapping of single Drosophila mushroom body neurons |
|
Hancock CE, Geurten BRH, Fiala A |
STAR Protocols |
2020 |
|
|
| Neural computation underlying rapid learning and dynamic memory recall for sensori-motor control in insects |
|
Rapp H, Nawrot MP |
bioRxiv |
2020 |
|
|
| A mechanistic model for reward prediction and extinction learning in the fruit fly |
|
Springer M, Nawrot MP |
bioRxiv |
2020 |
|
|
| Numerical Cognition Based on Precise Counting with a Single Spiking Neuron |
|
Rapp H, Nawrot MP, Stern M |
iScience |
2020 |
|
|
| A Plausible Mechanism for Drosophila Larva Intermittent Behavior |
|
Sakagiannis P., Aguilera M., Nawrot MP. |
Conference on Biomimetic and Biohybrid Systems. Living Machines |
2020 |
|
|
| One-trial learning in larval Drosophila |
|
Weiglein A, Gerstner F, Mancini N, Schleyer M, Gerber B |
Learning & Memory |
2019 |
|
|
| Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner |
|
Bhukel A, Beuschel CB, (...), Sigrist SJ |
Nature Communications |
2019 |
|
|
| Numerical cognition based on precise counting with a single spiking neuron |
|
Rapp H, Nawrot MP, Stern M |
bioRxiv |
2019 |
|
|
| Neuronal processing of amino acids in Drosophila: from taste sensing to behavioural regulation |
|
Toshima N, Schleyer M |
Current Opinion in Insect Science |
2019 |
|
|
| Timing-dependent valence reversal: a principle of reinforcement processing and its possible implications |
|
Gerber B, König C, (...), Yarali A |
Current Opinion in Behavioral Sciences |
2019 |
|
|
| An optogenetic analogue of second-order reinforcement in Drosophila |
|
König C, Khalili A, Niewalda T, Gao S, Gerber B |
Biology Letters |
2019 |
|
|
| Visualization of a Distributed Synaptic Memory Code in the Drosophila Brain |
|
Bilz F, Geurten BRH, Fiala A |
Social Science Research Network |
2019 |
|
|
| In Vivo Optical Calcium Imaging of Learning-Induced Synaptic Plasticity in Drosophila melanogaster |
|
Hancock CE, Bilz F, Fiala A |
Journal of Visualized Experiments |
2019 |
|
|
| Reversal learning in Drosophila larvae |
|
Mancini N, Hranova S, (...), Gerber B |
Learning & Memory |
2019 |
|
|
| Modulations of microbehaviour by associative memory strength in Drosophila larvae |
|
Thane M, Viswanathan V, Meyer TC, Paisios E, Schleyer M |
PLoS One |
2019 |
|
|
| Modulators of hormonal response regulate temporal fate specification in the Drosophila brain. |
|
Marchetti G, Tavosanis G |
PLoS genetics |
2019 |
|
|
| Cockroaches Show Individuality in Learning and Memory During Classical and Operant Conditioning. |
|
Arican C, Bulk J, Deisig N, Nawrot MP |
Frontiers in Physiology |
2019 |
|
|
| Studying complex brain dynamics using Drosophila |
|
Aimon S, Grunwald Kadow IC |
Journal of Neurogenetics |
2019 |
|
|