Welcome to the Research Data Platform of the DFG Research Unit FOR 2705

Dissection of a Brain Circuit: Structure, Plasticity and Behavioral Function of the Drosophila Mushroom Body

Latest publications:

Baltruschat L, Prisco L, Ranft P, Lauritzen JS, Fiala A, Bock DD, Tavosanis G. Circuit reorganization in the Drosophila mushroom body calyx accompanies memory consolidation. Cell Rep. 2021 Mar 16;34(11):108871. doi: 10.1016/j.celrep.2021.108871. PMID: 33730583.

Pooryasin A, Maglione M, Schubert M, Matkovic-Rachid T, Hasheminasab SM, Pech U, Fiala A, Mielke T, Sigrist SJ. Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila. Nat Commun. 2021 Mar 26;12(1):1932. doi: 10.1038/s41467-021-22180-6. PMID: 33771998; PMCID: PMC7997984.

Springer M, Nawrot MP. A Mechanistic Model for Reward Prediction and Extinction Learning in the Fruit Fly. eNeuro. 2021 Jun 16;8(3):ENEURO.0549-20.2021. doi: 10.1523/ENEURO.0549-20.2021. PMID: 33785523; PMCID: PMC8211469.

Our Research Topic

A fundamental scientific problem of our time is to understand how brains integrate present sensory stimuli, past experience, and future behavioral options. Our research unit investigates how adaptive behavior is organized through the properties of single neurons, their synapses, and the neural circuits the neurons are part of. We focus our research on the mushroom body of the Drosophila brain as an ideal study case.